Types of cholesterol-lowering drugs. Drug therapy is a major player in the fight against heart disease and there are many cholesterol-lowering medications at your doctor's disposal -- each with its own set of of adverse reactions. Some can be used alone or along with a statin to help patients reach their cholesterol targets. Statins continue to provide the most effective lipid-lowering treatment in most cases. Non-statin cholesterol-lowering medicines work in different ways. The first line class of medications -- the statins pose the greatest risk of damage to the liver. Statins are recommended for most patients and have been directly associated with a reduction in the risk of heart attack or stroke. However, the U.S. Food & Drug Administration no longer recommends routine monitoring for statin users. https://www.wikihow.com/Control-Cholesterol-Without-Statins “Our goal in treating cholesterol is to get it as low as possible based on the patient's individual risk, so it's not uncommon to use two medications together to optimize somebody's health,” says Dr. Phillips. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. The company has also applied for FDA approval to use the drug as a combination pill with ezetimibe, another non-statin. Since their treatment options are limited, supplements may help further reduce cholesterol levels. If you decide to take cholesterol medication, your doctor might recommend periodic liver function tests to monitor the medication's effect on your liver. In studies, that combination reduced cholesterol … There was a total of 879 subjects allocated to receive dual lipid-lowering therapy (statin plus ezetimibe or PCSK9 inhibitors) and 880 subjects allocated to the respective control arms (statin monotherapy). Various medications can lower blood cholesterol levels. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Many patients who can’t take statins will take non-statin drugs like ezetimibe and PCSK9 inhibitors. Muscle pain is one of the most common side effects associated with statins. Eight eligible trials of non-statin lipid-lowering drugs, including 1759 patients, were identified and considered eligible for the analyses.
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